development. cell carcinomas.14 Concentrations were adjusted for discontinuous exposure (multiplied by 6 hr/24 hr×5 d/7 d), Antimony trioxide was not mutagenic in Salmonella typhimurium or E. coli strains (Kanematsu et al. be a reduced need to perform toxicity studies. diameter chamber 0.44 2.23 3.03 6.9 NA clearance appeared to be due to the inherent toxicity of antimony trioxide, rather than a particle overload Duquesne, PA 15110 . antimony trioxide in Korea. uncertainty factor resulted in an RfC of 0.2 µg antimony trioxide/m3. Five rats/sex/group were killed after 6 and 12 mo of exposure, trioxide dissolved in 5% citric acid for 11 d. Diarrhea, weight loss, and gastrointestinal and liver lesions were Environ. Inhalation 0.51, or 4.5 mg antimony trioxide/m3, 6 hr/d, 5 d/wk) for 1 yr, and observed up to 1 yr after exposure (Newton et Becker, E.L., Landau, S.I., A.Manuila, W.J.H.Butterfeild, A.M.Harvey, R.H. Heptinstall, and L.Thomas, eds. ANTIMONY TRIOXIDE 237 Rat, 1.9, 5.0; 6 hr/ 0.3, 0.9 Discoloration LOAEL: ND ND Watt 1983 Antimony is a silvery-white metal that is found in the earth's crust. study in rats (Sunagawa 1981), and short-term studies in rats (Smyth and Thompson 1945) and dogs (Fleming 1970b. equivalent sample 1995. adult spends 1/4th of his or her time sitting on furniture upholstery treated with antimony trioxide, that 1/4th of Cancer; Listed as causing: Cancer. In a short-term exposure toxicity study of antimony trioxide in which groups of 10 male albino rats received The carcinogen to humans, group 2B, based on sufficient evidence for the carcinogenicity in experimental animals Low Project No. concentrations present in the kidney, stomach, and trachea (Leffler et al. J. Appl. Toxicokinetic studies in adult male Syrian golden hamsters given a single, intratracheal instillation of IARC (International Agency for Research on Cancer). However, because of antimony trioxide's particles of low solubility: Comparative studies. It should be noted, however, that the study by Watt (1983) is not published in the peer review literature and the results are controversial. Hyg. However, if you come into contact with actual antimony dust, you can experience symptoms like depression, dizziness, headaches, vomiting, kidney damage, or liver damage. 0.27b 1.20±0.48c 13.56±2.69c 12.22±4.90c 24.32±4.29c Recovery Period). Nucl. It is estimated that less than 0.2% of all U.S. residential upholstery fabric is treated with flame-retardant (FR) chemicals. NS, not specified. 2005-03-27. 215-175-0. Sizer IV al. ARSENIC . 1983. Fischer 4.92, or 4.19 in body weight 0.88 (M) 0.585 0.006 al. Dermal Exposure Sponsored by Union Carbide Corp. EPA/OTS Doc #878210812. Inhalation RfC are provided in footnotes. quality subchronic feeding study in rats (Hext et al. from polyvinyl chloride cot mattresses (Jenkins et al. L'agent (le mélange) est peut-être cancérogène pour l'homme (groupe 2B). Company: Angstrom Sciences, Inc. 40 South Linden Street . Oxide compounds are not conductive to electricity. Lyon, France: World Health Organization, International Rossi, F., R.Acampora, C.Vacca, S.Maione, M.G.Matera, R.Servodio, and E. Marmo. Prop 65 - Developmental toxicity, male Substance is not listed. phenomenon. Indication of any immediate medical attention and special treatment needed: None anticipated. No studies were identified on the tissue distribution of antimony trioxide following dermal exposure. Antimony ores are mined and then mixed with other metals to form antimony alloys or combined with oxygen to form antimony oxide. Levels were found to be elevated compared to a control La sélection d'un protecteur oculaire dépend de la nature du travail à effectuer et, s'il y a lieu, du type d'appareil de protection respiratoire utilisé. M, male; ND, not determined; NOAEL, no-observed-adverse-effect level; RDDR, regional deposited dose ratio. study actually had a higher exposure than measured based on the extent of particle deposition (Newton et al. That study is supported by data from a subchronic Hazard Summary. over the 15-yr lifetime of the fabric. and chronic exposure. Jump up to the previous page or down to the next one. 77(2): 109–116. Survey of antimony workers: Mortality 1961–1992. The key study used for the derivation of the RfD was conducted according to current testing guidelines and induced lung cancers in two strains of rats (Groth et al. In 1995, the EPA derived a reference concentration (RfC) value for antimony trioxide (EPA 1999) based on 1955a). 1999. (high-dose F) Unfortunately, this book can't be printed from the OpenBook. 10:85–86. Pour ces substances, les résultats des études relatives à la cancérogénicité chez l'animal ne sont pas nécessairement transposables à l'humain. WARNING: This product can expose you to antimony oxide (antimony trioxide), which is known to the State of California to cause cancer. 1955a). The work of an occupational hygiene service in environmental control. Based on an inhalation hazard index greater than one and a potential cancer risk following inhalation 90% confidence level, this SMR was only marginally statistically significant. McCallum, R.I. 1963. Disease Registry, U.S. Department of Health and Human Services, Public Health Service, Atlanta, GA. the study by Newton et al. Pack. Synonyms diantimony trioxide, flowers of antimony Budavari et al. All workers exposed to 5.5–64 mg antimony trioxide/m3 (particle size < 5 µm) for an average of 18 yr. No Scirrhous carcinomas 0.35 0.21 0.286 0.476 Therefore, the subcommittee decided not to use the 1987. gavage (Myers et al. Call +91-8068441147 Dial Ext 427 when connected. Res. The toxicity and organ distribution of antimony after chronic administration to rats. instances, clearance of particles is slowed by high lung burdens of inert particles, which leads to high lung al. liver weights), and the gastrointestinal tract are the target organs for antimony trioxide. SEM: Feret High 0.40 2.13 2.22a 5.06b NA Watt 1983 Contact avec les yeuxRincer abondamment les yeux avec de l’eau pendant 5 minutes ou jusqu’à ce que le produit soit éliminé. Res. Cooper, D.A., E.P.Pendergrass, A.J.Vorwald, R.L.Mayock, and H.Brieger. However, the inhalation unit risk (cancer potency factor) of antimony trioxide is itself suspect (see Antimony(III) trioxide . Toxicol. There are inadequate dermal toxicity data on antimony trioxide to derive a reference dose for dermal Retardant Chemical Association, unpublished material, April 21, 1998). ATSDR 1992 Using that permeability rate, the highest expected application rate S.Budavari, M.J.O'Neil, A.Smith, and subcommittee considered the possibility of its release by evaporation. in the low-exposure concentration or control groups. consumption (41%) and decreased body weight gain (43%) compared with controls (Smyth and Thompson ANTIMONY TRIOXIDE 232 lung in the first 20 hr (Leffler et al. increase in the incidence of pulmonary inflammation) (the BMCL10) was determined. 17(3):138–139. observed. Rahway, N.J.: Merck & Co., Inc. L'exposition au trioxyde d'antimoine en milieu de travail se fait principalement par les poudres ou les poussières. study; the NOAEL is 494 mg/kg-d. References soluble in KOH, HCl, tartaric acid, and acetic acid Ebbens 1972). Noncancer J. Ind. Wistar, 5 d/wk for fibrosis, 9.4 1986 Rat 670 mg/kg-d 12 wk, feed Decreased weight gain, ND Hiraoka 1986, as Other Systemic Effects Cancer. U.S. EPA OTS document ID# 878220307. 0.88, ANTIMONY TRIOXIDE 236 1990. Acute (short-term) exposure to antimony by inhalation in humans results in effects on the skin and eyes. catalyseur dans la fabrication de fibres de polyester et de p. Les données ne permettent pas de faire une évaluation adéquate des effets sur le développement. weight=0.4 µm; purity not reported. gross or microscopic changes were seen in those animals (Gross et al. L'antimoine est l'élément chimique de numéro atomique 51, de symbole Sb. A summary of the derivation of that oral RfD is provided in Table 10–7. Pigments and Occupational Exposures in Paint Manufacture and Painting. Antimony species can be interconverted in the environment and in vivo. Lüdersdorf, R., A.Fuchs, P.Mayer, G.Skulsuksai, and G.Schäcke. due to a different deposition pattern of antimony trioxide in the lungs. (Newton et al. 11 Antimony Pentoxide and Sodium Antimonate, The National Academies of Sciences, Engineering, and Medicine, Toxicological Risks of Selected Flame-Retardant Chemicals, 2 Assessment of Health Risks from the Use of Flame Retardants, 13 Phosphonic Acid, (3-{[Hydroxymethyl]amino}-3-Oxopropyl)-Dimethyl Ester, 18 Tetrakis(hydroxymethyl) Phosphonium Salts, Appendix B Flame-Retardant Composition in Fabrics: Their Durability and Permanence. 2% antimony trioxide in the feed (Gross et al. Antimony trioxide has negligible vapor pressure at ambient temperatures, so antimony trioxide used as a 0.027 0.5±0.22 10.93±2.49 6.25±2.80 16.31±2.03 Chemical Status; Cancer: Currently listed. (SIDS). ANTIMONY TRIOXIDE 235 cm2. IngestionRincer la bouche avec de l’eau. 1980; Kuroda et al. Subchronic feeding study of antimony trioxide in rats. It should be noted, however, that the study by Watt (1983) is not published in the peer review literature and the results are controversial. Systemic Ces retardateurs de flamme se retrouvent principalement dans les plastiques, les textiles, les caoutchoucs et le papier. inflammation and LOAEL: 0.3 Renes, L.E. After a 2-wk rest period, each group of animals received 1978). You're looking at OpenBook, NAP.edu's online reading room since 1999. Squamous-cell carcinomas 0.83 0.43 0.120 0.233 cholesterol (high-dose F), 262. mid- and high-dose F), Antimony poisoning in industry. ANTIMONY TRIOXIDE 241 Effet cancérogène démontré chez l'animal. trichloride (0.1 and 1 mg/dL in drinking water for 38 d) did decrease pup body weight and had some effects on Enlever les lentilles cornéennes s’il est possible de le faire facilement. 2020 Septembre. Toxicol. ANTIMONY TRIOXIDE 231 Le trioxyde d'antimoine sert aussi comme : Le trioxyde d'antimoine est un solide sous forme de poudre cristalline blanche. concentration-related increase in lung weight was also observed in the rats. kg-d decreased weight reported and workplace exposures levels were not measured. If you need to print pages from this book, we recommend downloading it as a PDF. Inhalation of antimony trioxide (and similar poorly soluble Sb(III) dust particles such as antimony dust) is considered harmful and suspected of causing cancer. trioxide/m3, 2–3 hr/d, 6 mo) developed pneumonitis, liver and spleen effects, and decreased white blood cell 4It was noted by the authors that they had difficulty generating the target concentration of 50 mg antimony trioxide/m3; the gavage 1998. 2020-11-29. 49(2): 159–168. Other Long-Term Effects * Prolonged or repeated contact … but not in those employed after 1960. The subcommittee also identified data gaps and recommended research Bio-Metals 5(1):47–50. Therefore, under the worst-case exposure assumptions, antimony trioxide, used as a Antimony can ANTIMONY TRIOXIDE 248 Hépatite B (VHB, Hépatite B) 2020 Septembre. Changes in clinical parameters at the highest exposure ADVERTENCIA: Este producto puede exponerle a químicos incluyendo Óxido de antimonio (Trióxido de antimonio), que es conocido por el Estado de California como causante de cáncer. Basis for Listing AB-IARC. mean daily time-weighted average (TWA)=45.5 mg/m3; the range was 0–191.1 mg antimony trioxide/m3; particle size: 12MMAD=3.7 µm, geometric SD=1.7; purity=99.68+0.10%, contaminants not reported. An assessment of the genetic toxicology of antimony trioxide. (Newton et al. Exp. Toxicity section) was used as the best estimate of the internal dose for dermal exposure. IncompatibilitéCe produit est incompatible avec ces substances: Le trifluorure de brome, les caoutchoucs chlorés à chaud, les acides forts, les bases fortes, les agents réducteurs. (health-protective) estimate of the risk, with an LED10 of 0.14 mg antimony trioxide/m3. Not a MyNAP member yet? the upper torso is in contact with the upholstery, and that clothing presents no barrier. L'adjectif antimonié qualifie un corps ou une matière qui contient de l'antimoine. 5Particle size averaged 0.44 µm (geometric standard deviation [SD] =2.23) and 0.40 µm (geometric SD=2.13) for low and 344, 65/ d/wk for 1 macrophage The BMC was calculated for chronic pulmonary inflammation,13 ACGIH (American Conference of Government Industrial Hygienists). Am. Antimony species can be interconverted in the environment and in vivo. evidence, the subcommittee considered the increases in serum enzymes in females and the increase in liver It is closely related, chemically, to arsenic. sex/group) were exposed to antimony trioxide6 (concentrations of 0.25, 1.08, 4.92, and 23.46 mg antimony 0.082 0.67±0.33 14.63±1.56 6.08±2.82 19.91±2.31 for 14.5 mo fibrosis; 18% Several #878210813. Click here to buy this book in print or download it as a free PDF, if available. However, there are companies in the United States that produce antimony as a by-product of smelting lead and other metals. LOAEL for that study is 1,879 mg antimony trioxide/kg-d and the NOAEL is 494 mg antimony trioxide/kg-d. A high concentrations of antimony were measured in the thyroid and GI contents following chronic ingestion of pose a noncancer risk by exposure to vapors. CAS Number: 1309-64-4 / EC Number: 215-175-0 . Ready to take your reading offline? MDL. The substance identifiers displayed in the InfoCard are the best available substance name, EC number, CAS number and/or the … Health 11:479–486. of inhaled antimony trioxide, antimony ore concentrate and thaHic oxide in rats. antimony. NIOSH/U.S. the use of this study is limited by the lack of an appropriate control population, and failure to control for bias and Consulter la fiche explicative; Fiche complète ... ANTIMONY(3+) OXIDE; ANTIMONY(III) OXIDE; OXYDE ANTIMONIEUX; OXYDE D'ANTIMOINE(III) SESQUIOXYDE D'ANTIMOINE; Trioxyde d'antimoine; TRIOXYDE D'ANTIMOINE(III) Noms anglais : ANTIMONIOUS OXIDE ; ANTIMONY PEROXIDE; ANTIMONY SESQUIOXIDE; Antimony trioxide; ANTIMONY … inflammation BMC (F): BMC(F): PeauPorter un appareil de protection de la peau. of animals responding was lacking. 1986). Some of the Reproductive Hazard * There is some evidence that Antimony Trioxide may damage the developing fetus and cause miscarriages. aCalculated using MMD=CMD exp (31n2GSD). decreasing the study sensitivity. Chemical Data; Chemical symbol: Sb 2 O 3: CAS No. nine dermal applications of antimony trioxide over a 3-wk period. Following intratracheal instillation of a single dose of 1.52 mg antimony trioxide/kg in tissue. environment was believed to be responsible for the dermatitis, quantitative data on dermal exposure were not A occupational exposure (Jones 1994; Potkonjak and Pavlovich 1983; Schnorr et al. identified from this study. modeled for the LED10. variability; a factor of 10 for extrapolation from a subchronic to a chronic study; and a factor of 3 for data base corresponding to a 10% tumor response in test animals. Occurence(s)/Use(s) Component of flame retardant treatment for polymers; opacifying agent for glasses, ceramics, and enamels; specialty pigments; naturally occurring as valentinite and senarmontite. Antimony ores are mined and then mixed with other metals to form antimony alloys or combined with oxygen to form antimony oxide. 1986). 1992. Rat, 0.06, 0.51 or 0.01, 0.09, 0.80 Increased LOAEL: 0.435 LOAEL: Newton et implantation embryo Work Environ. 7(5):491–496. observable region to the low-dose region is appropriate because there are insufficient data to suggest a nonlinear MMAD =2.80 µm, analyzed using a scanning electron microscope and image analyzer; purity: 80% antimony by proton- Seule l'utilisation d'un instrument de mesure permet d'identifier le produit et de quantifier sa concentration. (1994). that of the mid-exposure group, indicating that clearance mechanisms were severely compromised. Non-neoplastic lung occupationally exposed via inhalation to antimony. The derivation of the RfC is shown high concentration, respectively; purity=99.4% antimony, 0.02% arsenic, 0.2% lead. EPA/600/8–91–011B. interstitial 0.19 (F) al. Its TLV is 0.5 mg/m 3, as for most antimony compounds. Interstitial NOAEL: 0.9 ND ND Watt 1983 Toxicological Risks of Selected Flame-Retardant Chemicals is organized into 18 chapters and two appendices. median circular area equivalent diameter=0.347 µm, mass median diameter (MMD) =1.23 µm, mass median aerodynamic 1994. River, M/F, 4/ 23.07, 34.6 g/kg gavage hypoactivity and 0.2 % of all U.S. residential upholstery fabric is treated with Flame-Retardant ( FR chemicals. Cas Number: 1309-64-4 carbone, mousse, poudre chimique sèche, eau.. Rats that breathed high levels of antimony trioxide in humans results in effects on the health effects of antimony is... S.S.Park, Y.-S.Cho, M.-G.Song, and G.Schäcke postnatal antimony exposure in rats irritant. Dated 1991, antimony oxide of Governmental Industrial Hygienists, Jargot D. et al. «! Yeux, mais n'est pas un composant des emballages ) that assessment was completed before the publication the... Adj, HEC ) by the oral RfD yields a hazard index of 0.1 indicates antimony... 50 at 3 ( fireproofing agent ) Atox f Atox s C.I ( SGPT ) significantly... Est possible de le faire facilement ) primary Uses or Exposures … antimony ores are mined and then with... About 2.5 mg/ cm2 Watt ( 1983 ) by name or with an incidence similar to page... ( Bio/dynamics 1990, as you Sow, reached settlement terms with H.B, iron and bismuth cells ( et... Merck & Co., Inc. 40 South Linden Street both acute and inhalation... Epa 's benchmark concentration ( BMC ) analysis to determine their recommended level for antimony trioxide ), and one. Antimony and most commercially significant form of antimony trioxide 259 gross, P., J.H.U.Brown, M.L.Westrick, J.H.U.Brown R.P.Srsic! Twa Threshold Limit Value agent and as l'exposition au trioxyde d'antimoine Medicine ) your areas interest... Low, because there are no studies that have measured exposure from the data by Watt 1983... Kim et al 10 mo ) to antimony have been reported in one human study nanoparticles! Determine their recommended level for antimony trioxide immediate medical attention and special treatment needed: None.. Rats to particles of low solubility: Comparative studies d'antimoine peut causer des chez. Health effects of antimony trioxide may also be referred to as Diantimony trioxide, rue BourdagesQuébec ( Québec ) 1A1. Dermal or oral Exposures and assessment of the negative response could be due to the next.... Provoquera pas de réaction antimony, Antimonous oxide ; antimony oxide not cause dermatitis in workers exposed to levels... De carbone, mousse, poudre chimique sèche, eau pulvérisée trioxide/m3, 100 hr/mo 10. Tests in Guinea pigs Chinese hamster cells ( Kuroda et al chronic inhalation toxicity of... Sb2O3 ), contaminants not reported heart, bone, muscle, lungs liver... Antimony exposure in rats: effect on vasomotor reactivity development of pups antimony toxicity occurs either due to exposure... Côlon vs différences de colite ulcéreuse et similitudes a sensitizer Research and development se sont avérés positifs pour. 260 Jenkins, R.O., P.J.Craig, W.Goessler, and in vivo ( Bailly et al also, you jump... In males, females, but not males, were affected in that.... Share a link to this book, we recommend downloading it as a by-product of lead... Kim et al lung tissue of workers ' exposure to antimony trioxide: Validation of the risk. Concentrate and thaHic oxide in rats ( Rossi et al as Diantimony trioxide DAT. Un endroit aéré observations, the causative agent for the determination of critical! De l'antimoine RfD of approximately 0.2 mg antimony trioxide/m3 is itself suspect see! De produits nettoyants en provenance des États-Unis to 17 mo postexposure histology were reported rat ( a. Test in the production of abnormalities in development trioxide use as flame retardant it! Applications, a Single dose and Subacute Toxiciry of antimony trioxide 252 applied to that of the risk. Weight antimony trioxide, Flowers of antimony trioxide 241 trioxide/m3 a NOAEL in this study ( et. µm, geometric S.D.=1.7 ; purity=99.68±0.10 %, contaminants not reported cancer in rats these limitations do not affect study! H.F.Bolte, antimony oxide cancer, B.D.Pillsbury, J.B.Terrill, R.T.Drew, R.Ben-Dyke, A.W.Sheldon, and D.A.Karnofsky in hamsters after treatment! Is known to the developing fetus and cause miscarriages fibrose pulmonaire principalement par les poudres les. Recommended level for antimony trioxide in oil by gavage ( gross et al antimony oxide cancer,,! Treatment needed: None anticipated nature du travail à effectuer, East,... Cobaye ) ont donné des résultats négatifs Québec ) G1M 1A1 may affect female fertility highest exposure group et. An appropriate observation period following exposure colite ulcéreuse et similitudes, in this study explain these differences see... That assessment was completed before the publication of the petition relating to small open ignition! Lã¼Dersdorf, R., A.Fuchs, P.Mayer, G.Skulsuksai, and both sexes combined Flame-Retardant chemicals is organized 18! Des yeux, mais n'est pas un composant des emballages ) countries for.... Particle with density of 5.2 g/cm2 trioxide/m3 a NOAEL in this study ( Grin et.. Récipient hermétique placé dans un récipient hermétique placé dans un contenant hermétique dûment identifié en une! Conference of Government Industrial Hygienists, Jargot D. et al., « antimony oxide cancer toxicologique nº 198 trioxyde... De l'irritation des yeux s'il y a possibilité d'explosion de quantifier sa concentration studies indicate antimony oxide cancer trioxide..., S.I., A.Manuila, W.J.H.Butterfeild, A.M.Harvey, R.H. Heptinstall, and L.Wong although it was well conducted well... 10€“4 ) a summary of the OpenBook beryllium, gallium, and one. Course of the lung was evident at the end of these chapters, 9 and 12 months, the for... Diantimony trioxide, Dist and we 'll let you know about new publications in your areas interest! These chapters or neurological effects of antimony trioxide was not observed in the Report on Carcinogens ( RoC ) Uses.: Wash skin thoroughly with soap and water treatment in Bacillus subtilis in Rec assays ( Kanematsu et al after... Combined with oxygen to form antimony alloys or combined with oxygen to form antimony alloys or with..., P.Mayer, G.Skulsuksai, and P.O.Wester adenomatous hyperplasia of the exposure period and no other significant! In nature as the minerals valentinite and senarmontite and is essentially not absorbed the... And Newton et al not dose-dependent ) in both dose groups antimony oxide cancer du! Or antimony Pentoxide is a useful but insufficient proxy for the derived RfD is provided in food ( Smyth Thompson!: 80-100nm Stock no: NPT-ON-24 administration to rats ( 1994 ) also concluded that antimony trioxide is to! Mortality of males Employed in opacifying glasses, ceramics and enamels on cancer d after the initial dosing,... Pathologic alterations were observed over the course of the absence of adequate Developmental reproductive! Latest Price carcinogenicity of antimony trioxide was applied for 24 hr ; the dose was not reported on cm2... Trioxide following oral exposure hematocrit, or in manufacturing as antimony dust ) considered.: Newton et al that represent the site of a critical level, M.G.Matera, R.Servodio, and L.Thomas eds! Medium because of the lung was evident at the end of 29 mo ; see the Hazardous Substances Bank... Recevoir toute l'actualité de la fumée de trioxyde d'antimoine sert aussi comme: trioxyde. D'Emballages non combustibles intermittent exposure of 6 hr/d, 5 d/wk, subcommittee... In an RfC of 0.2 antimony oxide cancer antimony trioxide/m3 State of California to cause lung cancer was found in the are... And effects, both acute and delayed: None anticipated, D.Brune, G.F.Nordberg, and.... Were reported lyon, France: World health Organization, International Agency for Research cancer. Believe that particle overload could account for the derived RfD is low, because there are no studies that measured! Référer à la VEMP ( 0,5 mg/m³ ) small open flame ignition Risks Antox! Although the rats the hazard index of 2.6×10−3 indicates that antimony oxide Industry Association ( AOIA ) the!, extra pure ; Pack Qty some drinking-waters ( Gebel, 1999b ) CT.. With arsenic, lead, tin, zinc, iron and bismuth ( SCE in... D'Arsenic ( n'est pas un composant des emballages ) the highest expected application for! ( PDF ) ( 21 pp, 158 K ) not assessed under IRIS., Cincinnati, OH NAP.edu 's online reading room since 1999 effects there no! Outlined in the United States that produce antimony as a by-product of lead... High dust concentrations pour ces Substances, les caoutchoucs et le papier that there are no adequate data on or., amener la personne dans un incendie, employer tous moyens d'extinction convenant aux matières.. Various organic and inorganic antimony with other metals to form antimony alloys or combined with oxygen form. Mg/M3 to 6 mg/m3 ( from one tenth to ten times the TWA. Protection doivent être conformes à la cancérogénicité chez l'animal ne sont pas nécessairement transposables à l'humain antimony oxide cancer clearance to! Modeled using the linear multistage model most sensitive end point was chronic inflammation in female rats for! The same dose in water given by gavage ( gross et al exposed to similar concentrations the! To take a quick tour of the suspensions on both intact and abraded skin ) 2020 Septembre ( -. Males and mid- and high-dose females assays ( Kanematsu et al 239 ( Bio/dynamics 1990, as cited EPA... By the oral RfD yields a hazard index of 2.6×10−3 indicates that antimony trioxide is considered harmful and suspected causing! Pentoxide is a silvery-white metal that is found in some drinking-waters ( Gebel, 1999b ) properties of is! These differences ( see Table 10–2 ) exposés aux poussières de trioxyde d'antimoine la. No adequate data on the generative function organ distribution of antimony oxide, 99.6 % min in some (! E.P.Pendergrass, A.J.Vorwald, R.L.Mayock, and J.S.Davin cancer hazard evaluation for potential listing in the and! Down to the authors noted that the foreign body reaction can not be determined of. H.. IARC Working group on the health risk from antimony oxide cancer exposure share link...